Opportunity Information: Apply for HT942526OCRPIIRA
The Department of the Army, through the U.S. Army Medical Research Acquisition Activity (USAMRAA), is offering the Ovarian Cancer Research Program (OCRP) Investigator-Initiated Research Award (funding opportunity number HT942526OCRPIIRA; CFDA 12.420). This discretionary grant opportunity is designed to fund high-impact, investigator-driven research that tackles a critical need in ovarian cancer and is positioned to make a meaningful contribution either to scientific understanding of the disease or to the care and support of patients and survivors. The program emphasis is on projects that can move the field forward in a substantive way rather than incremental extensions of existing work.
A defining requirement is a strong, well-justified research plan grounded in sound scientific rationale and clear, logical reasoning. Applications are expected to be rigorous in their approach and to demonstrate that the proposed work is feasible and well supported by evidence. Preliminary data are explicitly required, which signals that the funder is looking for projects that already have a foundation of proof-of-concept results and are ready for a focused, well-constructed next phase. In terms of scope, the award supports research across the pipeline, ranging from basic laboratory studies through translational research. However, clinical trials are excluded, so applicants should frame proposed human-facing work (if any) as preclinical, translational, or otherwise short of an interventional clinical trial.
The opportunity also includes a Partnering Principal Investigator option. Under this structure, two investigators are both formally designated as PIs and are expected to work together in a genuinely synergistic way on one integrated project. The intent is not parallel, loosely connected subprojects, but a collaborative design where the combined expertise, resources, or methods of both PIs enable outcomes that would not be achievable through either investigator working alone. The application should make it clear how responsibilities are shared, how the partnership strengthens the scientific approach, and why the expected results will significantly advance the research beyond what individual efforts could produce.
Administratively, the opportunity is categorized as a grant under the Science and Technology and other Research and Development activity area, with eligibility listed as unrestricted, indicating a broad applicant pool without narrow institutional constraints in the posted summary. The original closing date is October 1, 2026, and the agency anticipates making about 14 awards. The award ceiling is not specified in the provided source details, so applicants would need to consult the full announcement for budget limits, allowable costs, period of performance, and any OCRP-specific submission requirements. Overall, this funding opportunity is best suited for investigators with a clearly articulated ovarian cancer research question, supportive preliminary results, and a project plan capable of delivering a high-impact advance in biology, detection, prevention, or patient/survivor-centered care, while staying outside the scope of a clinical trial.Apply for HT942526OCRPIIRA
- The Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoW, Ovarian Cancer, Investigator-Initiated Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
- This funding opportunity was created on 2026-05-04.
- Applicants must submit their applications by 2026-10-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 14 candidate(s).
- Eligible applicants include: Unrestricted.
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Frequently Asked Questions (FAQs)
What is this funding opportunity?
This opportunity is the Department of the Army Ovarian Cancer Research Program (OCRP) Investigator-Initiated Research Award, administered through the U.S. Army Medical Research Acquisition Activity (USAMRAA). The funding opportunity number is HT942526OCRPIIRA and the CFDA listing is 12.420.
What is the main purpose of the OCRP Investigator-Initiated Research Award?
The award is intended to support high-impact, investigator-driven research that addresses a critical need in ovarian cancer and is positioned to make a meaningful contribution to scientific understanding and/or the care and support of patients and survivors. The emphasis is on moving the field forward in a substantive way rather than funding incremental extensions of existing work.
What types of ovarian cancer research are encouraged?
Based on the description provided, projects should be framed as high-impact efforts that can significantly advance ovarian cancer research or patient/survivor support. The opportunity notes that projects may span the research pipeline from basic laboratory studies through translational research.
Does the award support basic science research?
Yes. The scope explicitly includes basic laboratory studies as part of the supported research pipeline.
Does the award support translational research?
Yes. Translational research is explicitly included within the supported scope.
Are clinical trials allowed under this award?
No. Clinical trials are excluded. Applicants should ensure that any human-facing components (if proposed) are framed as preclinical, translational, or otherwise not an interventional clinical trial.
Is preliminary data required?
Yes. Preliminary data are explicitly required. This indicates the funder is seeking projects with proof-of-concept or foundational results that justify the next stage of focused investigation.
What does the program mean by "high-impact" and "non-incremental" research?
The program emphasis is on research that can move the field forward in a substantive way, rather than small or incremental extensions of existing work. Applications are expected to demonstrate how the proposed study addresses a critical need in ovarian cancer and why the expected outcomes would meaningfully advance understanding, care, or support for patients and survivors.
What are the expectations for the research plan?
A defining requirement is a strong, well-justified research plan grounded in sound scientific rationale and clear, logical reasoning. Applications are expected to be rigorous, feasible, and well supported by evidence, with preliminary data serving as part of the justification.
What does "investigator-initiated" mean in this context?
The opportunity is described as investigator-driven, meaning the research question and approach are proposed by the applicant(s) rather than being limited to a narrowly prescribed set of project ideas. The project still needs to tackle a critical need in ovarian cancer and align with the program's emphasis on high-impact advances.
What is the Partnering Principal Investigator (PI) option?
The Partnering PI option allows two investigators to be formally designated as PIs on a single integrated project. They are expected to collaborate in a genuinely synergistic way, where the combined expertise, resources, or methods enable outcomes that would not be achievable by either PI working alone.
How should a Partnering PI application demonstrate synergy?
The application should clearly explain how responsibilities are shared, how the partnership strengthens the scientific approach, and why the combined effort will significantly advance the research beyond what individual efforts could produce. The intent is not loosely connected parallel work, but an integrated collaborative design.
Can the Partnering PI approach be used for parallel subprojects?
The description indicates that the intent is not parallel, loosely connected subprojects. The project should be integrated and collaborative, with clear justification that the partnership is essential to achieving the proposed outcomes.
Who is eligible to apply?
Eligibility is listed as unrestricted in the posted summary, suggesting a broad applicant pool without narrow institutional constraints. Applicants should still consult the full announcement for any additional eligibility requirements or conditions not included in the summary.
Which agency is offering and administering this opportunity?
The Department of the Army is offering the opportunity through USAMRAA (U.S. Army Medical Research Acquisition Activity).
What activity area or grant category does this fall under?
It is categorized as a grant under the Science and Technology and other Research and Development activity area.
What is the application deadline?
The original closing date listed is October 1, 2026.
How many awards does the agency expect to make?
The agency anticipates making about 14 awards.
What is the maximum award amount (award ceiling)?
The award ceiling is not specified in the provided details. Applicants would need to consult the full announcement for budget limits, allowable costs, the period of performance, and other OCRP-specific submission requirements.
What should applicants review in the full announcement that is not provided here?
Based on the summary, applicants should consult the full announcement for details such as budget limits (award ceiling), allowable costs, the period of performance, and any OCRP-specific submission requirements or instructions.
What kinds of outcomes or impact is this award looking for?
The award is aimed at projects likely to make a meaningful contribution to ovarian cancer science and/or to the care and support of patients and survivors. The proposal should show a clear path to a substantive advance, supported by rigorous rationale and required preliminary data.
What kind of project is this opportunity best suited for?
This opportunity is best suited for investigators who have a clearly articulated ovarian cancer research question, supportive preliminary results, and a feasible, rigorous plan capable of delivering a high-impact advance while remaining outside the scope of a clinical trial.
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